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CD177 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-01-03
  • 訪  問  量：87

詳細介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD177 Polyclonal Antibody detects endogenous levels of CD177 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human CD177. AA range:361-410

  • Uniprot No

    Q8N6Q3

  • Alternative names

    CD177; NB1; PRV1; CD177 antigen; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD177

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    CD177 molecule(CD177) Homo sapiens This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014],

  • Other

    CD177, CD177 antigen

  • Mol.Wt (Da)

    46363

  • Concentration

    1 mg/ml

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