CD101 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,ELISAReactivityHumanDilutionWB:1:500-1:2000

產(chǎn)品型號：
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2025-01-03
訪問量：97

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產(chǎn)品分類

CLASSIFICATION

Primary Antibodies

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詳細介紹

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

CD101 Polyclonal Antibody detects endogenous levels of CD101 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CD101. AA range:731-780
Uniprot No

Q93033
Alternative names

CD101; EWI101; IGSF2; V7; Immunoglobulin superfamily member 2; IgSF2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

function:Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.,PTM:N-glycosylated.,similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.,
Other

CD101, Immunoglobulin superfamily member 2; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101
Mol.Wt (Da)

115073
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

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上一篇：CD10 mouse mAb(5B8)
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CD101 rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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