您好，歡迎進(jìn)入上海貝博生物科技有限公司網(wǎng)站！
全國服務(wù)熱線

86-021-33921235

當(dāng)前位置：首頁   >  產(chǎn)品中心  >    /  Primary Antibodies  /  c-Cbl (phospho-Tyr731) rabbit pAb

c-Cbl (phospho-Tyr731) rabbit pAb

簡要描述：

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-01-03
  • 訪  問  量：100

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human

  • Dilution

    WB 1:1000-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Human c-Cbl (phospho-Tyr731)

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized phosho peptide around human c-Cbl (Tyr731)

  • Uniprot No

    P22681

  • Alternative names

    E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (Signal transduction protein CBL)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016],

  • Other

    CBL CBL2 RNF55, c-Cbl (Tyr731)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

產(chǎn)品咨詢

留言框

  • 產(chǎn)品：

  • 您的單位：

  • 您的姓名：

  • 聯(lián)系電話：

  • 常用郵箱：

  • 省份：

  • 詳細(xì)地址：

  • 補充說明：

  • 驗證碼：

    請輸入計算結(jié)果（填寫阿拉伯?dāng)?shù)字），如：三加四=7

  • 公司地址：上海市浦東新區(qū)

    公司郵箱：bestbio@163.com

    公司傳真：

  • 18930271235

    免費銷售熱線

    1722797799

  • 微信二維碼

    網(wǎng)站二維碼